Selection of excipients for the purpose of creating an intranasal gel of interleukin-1 receptor antagonist β (IL-1ra)

Selection of excipients for the purpose of creating an intranasal gel of interleukin-1 receptor antagonist β (IL-1ra)

There is a negative dynamic of the spread of cerebrovascular diseases, which often lead to disability or death in patients in the world, today. Such diseases are characterized by acute disorders of cerebral metabolism and blood circulation, against the background of other chronic pathologies. More t...

Full description

Bibliographic Details
Main Authors:	B. S. Burlaka, I. F. Bielenichev, V. V. Hladyshev, E. V. Suprun, H. P. Lysianska
Format:	Article
Language:	English
Published:	Zaporozhye State Medical University 2020-08-01
Series:	Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:	interleukin-1β (il-1ra) receptor antagonist release nasal dosage form
Online Access:	http://pharmed.zsmu.edu.ua/article/view/207190/207504

Similar Items

Thermogravimetric studies of a nasal preparation with an interleukin-1β (IL-1Ra) antagonist
by: B. S. Burlaka
Published: (2021-03-01)

Study of excipients influence on the noopept releasing from the nasal dosage form
by: B. S. Burlaka, et al.
Published: (2019-12-01)

Optimization of the composition of a nasal medicine with interleukin-1 antagonist β
by: B. S. Burlaka
Published: (2021-02-01)

Study of surfactants influence on the noopept releasing from the nasal dosage form
by: B. S. Burlaka, et al.
Published: (2020-05-01)

Differences in the Levels of Interleukin-1β (IL-1β) and Interleukin-1 Receptor Antagonist (IL-1ra) in Children with Status Epilepticus and Febrile Seizure
by: Fita Shofiyah, et al.
Published: (2017-09-01)

Avaliação da expressão de interleucina 1 beta (IL-1β) e antagonista do receptor de interleucina 1 (IL-1Ra) em pacientes com hanseníase Evaluation of the expression of interleukin 1 beta(IL-1β) and interleukin 1 receptor antagonist (IL-1Ra) in leprosy patients
by: Rosane Dias Costa, et al.
Published: (2008-01-01)

Severity evaluation of bhronic polypous rhinosinusitis based on changes of IL-1β cytokine and IL-1ra concentrations in nasal secretions
by: E. V. Bezrukova, et al.
Published: (2020-01-01)

Minimally-invasive Sampling of Interleukin-1α and Interleukin-1 Receptor Antagonist from the Skin: A Systematic Review of In vivo Studies in Humans
by: Denise Falcone, et al.
Published: (2017-06-01)

Negative Immunomodulatory Effects of Type 2 Porcine Reproductive and Respiratory Syndrome Virus-Induced Interleukin-1 Receptor Antagonist on Porcine Innate and Adaptive Immune Functions
by: Teerawut Nedumpun, et al.
Published: (2019-03-01)

INTERLEUKIN-1, INTERLEUKIN-6, AND ANTAGONIST INTERLEUKIN-1RECEPTOR AS MEMORY IMPAIRMENT RISK FACTOR IN COMPLEX PARTIAL EPILEPSY
by: D. P. G. Purwa-Samatra, et al.
Published: (2013-07-01)

Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture
by: Shikhar Mehta, et al.
Published: (2019-11-01)

The Role of Interleukin-1-Receptor-Antagonist in Bladder Cancer Cell Migration and Invasion
by: Lisa Schneider, et al.
Published: (2021-05-01)

Interleukin-1 receptor antagonist gene polymorphism in patients with multidrug-resistant Acinetobacter baumannii-associated pneumonia
by: Min-Jer Hsu, et al.
Published: (2012-01-01)

Mitoprotective effect of the receptor antagonist interleukin-1 in experimental cerebral stroke
by: E. V. Suprun
Published: (2012-12-01)

Imbalance Between Interleukin-1β and Interleukin-1 Receptor Antagonist in Epicardial Adipose Tissue Is Associated With Non ST-Segment Elevation Acute Coronary Syndrome
by: Valentina Parisi, et al.
Published: (2020-02-01)

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1β and IL-1ra production in multiple sclerosis
by: Hans M. Schrijver, et al.
Published: (2003-01-01)

Content of C-reactive protein, interleukin-1, interleukin-6 and interleukin-1 receptor antagonist in the blood of patients with early osteoarthrosis of the knee joints
by: M S Svetlova, et al.
Published: (2009-06-01)

Comparison of Oral Montelukast and Intranasal Fluticasone in Patients with Asthma and Allergic Rhinitis
by: Apar Jindal, et al.
Published: (2016-08-01)

Comparison of The Effect of Intra-Articular Injection of Autologous (Orthokine) Interleukin-1 (IL-1Ra) Receptor Antagonist and Hyaluronic Acid in Pain Control of Knee Osteoarthritis
by: Masoud Hashemi, et al.
Published: (2019-08-01)

Impact of the Functional VNTR Variants of the Interleukin-1 Receptor Antagonist and Interleukin-4 Genes on Oral Squamous Cell Carcinoma
by: Özge Gümüşay, et al.
Published: (2019-05-01)

EXCIPIENTS IN ORAL SUSPENSIONS
by: V. V. Vernikovsky, et al.
Published: (2019-01-01)

IL-1Ra Protects Hepatocytes from CCl4-Induced Hepatocellular Apoptosis via Activating the ERK1/2 Pathway
by: Ying Zheng, et al.
Published: (2020-06-01)

Effect of hypothermia on interleukin-1 receptor antagonist pharmacodynamics in inflammatory-sensitized hypoxic-ischemic encephalopathy of term newborns
by: Mathilde Chevin, et al.
Published: (2018-07-01)

Oxatomide inhibits Interleukin-8 release from respiratory epithelial cells
by: Hideyuki Kawauchi, et al.
Published: (2018-06-01)

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer
by: Nicole Armbruster, et al.
Published: (2017-05-01)

Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer
by: Razelle Kurzrock, et al.
Published: (2019-03-01)

A case report of a novel compound heterozygous mutation in a Brazilian patient with deficiency of Interleukin-1 receptor antagonist (DIRA)
by: Leonardo Oliveira Mendonça, et al.
Published: (2020-08-01)

Intranasal peptide absorption : mechanisms of enhancement
by: Chandler, Susan Gerrard
Published: (1992)

Evaluation of the Interleukin-1 Receptor Antagonist and Immunoregulatory Interleukin-10 in the Middle Ear in Chronic Otitis Media With Effusion in Children With and Without Atopy
by: Beata Zielnik-Jurkiewicz, et al.
Published: (2016-06-01)

Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression
by: Yu-Ching Fan, et al.
Published: (2020-12-01)

HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
by: V. V. Grebenyuk, et al.
Published: (2014-07-01)

IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes
by: Fen Wang, et al.
Published: (2019-07-01)

G-protein-coupled estrogen receptor activation upregulates interleukin-1 receptor antagonist in the hippocampus after global cerebral ischemia: implications for neuronal self-defense
by: Ning Bai, et al.
Published: (2020-02-01)

A Brief History of IL-1 and IL-1 Ra in Rheumatology
by: Jean-Michel Dayer, et al.
Published: (2017-05-01)

IMBALANCE OF IL -1β И IL -1RA CYTOKINES IN BLOOD SERUM AND BRONCHOALVEOLAR LAVAGE IN COPD PATIENTS
by: E. A. Surkova, et al.
Published: (2014-07-01)

The use of machine learning methods in the development of nasal dosage forms with cerebroprotective action
by: B. S. Burlaka, et al.
Published: (2021-07-01)

Thermogravimetric investigation of a new intranasal gel with noopept
by: B. S. Burlaka
Published: (2019-12-01)

Simvastatin and Recombinant Antagonist of Receptors of Interleukin-1 Modulate Toll-like Receptors in Experimental Acute Ileitis in Rat
by: Aleksandr Zherebiatiev, et al.
Published: (2014-08-01)

Low plasma levels of IGF-1 and IL-1RA with high plasma levels of IFN-γ as prognostic factor for mortality in hospitalized geriatric patients with delirium
by: I Nyoman Astika, et al.
Published: (2019-07-01)

Interleukin-1 Receptor Antagonist Modulates Liver Inflammation and Fibrosis in Mice in a Model-Dependent Manner
by: Raphael P. H. Meier, et al.
Published: (2019-03-01)

Cannot write session to /tmp/vufind_sessions/sess_1m7o5grs3jbp8k6okcn19806p0