Plant lessons: exploring ABCB functionality through structural modeling

Plant lessons: exploring ABCB functionality through structural modeling

In contrast to mammalian ABCB1 proteins, narrow substrate specificity has been extensively documented for plant orthologs shown to catalyze the transport of the plant hormone, auxin. Using the crystal structures of the multidrug exporters Sav1866 and MmABCB1 as templates, we have developed structura...

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Bibliographic Details
Main Authors: Aurélien eBailly, Haibing eYang, Enrico eMartinoia, Markus eGeisler, Angus S Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Plant Science
Subjects:
auxin
ABCB exporter
ABCB importer
Structural modeling
Substrate docking
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2011.00108/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2011.00108/full

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