Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)

Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes....

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Main Authors: Hamid Reza Hatamian, Babak Bakhshayesh, Nazanin Rahman-A
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2014-04-01
Series:International Clinical Neuroscience Journal
Online Access:http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4
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spelling doaj-14bd65874689477daead9f55059c0cd52020-11-24T20:53:50ZengShahid Beheshti University of Medical SciencesInternational Clinical Neuroscience Journal2383-18712383-20962014-04-0112697210.22037/icnj.v1i2.6754icnj-3044Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)Hamid Reza Hatamian0Babak Bakhshayesh1Nazanin Rahman-A2Department of Neurology, Guilan University of Medical Sciences, Guilan, IranDepartment of Neurology, Guilan University of Medical Sciences, Guilan, IranDepartment of Neurology, Guilan University of Medical Sciences, Guilan, IranPatients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. These lesions mimic infarction. Here, we reported a case of MELAS with rare neuroimaging finding of hemispheric cortical thickening on T2/FLAIR images with intracortical nodular gadolinium enhancement; then we discussed the clinical and radiological differential diagnoses of it.http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4
collection DOAJ
language English
format Article
sources DOAJ
author Hamid Reza Hatamian
Babak Bakhshayesh
Nazanin Rahman-A
spellingShingle Hamid Reza Hatamian
Babak Bakhshayesh
Nazanin Rahman-A
Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
International Clinical Neuroscience Journal
author_facet Hamid Reza Hatamian
Babak Bakhshayesh
Nazanin Rahman-A
author_sort Hamid Reza Hatamian
title Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
title_short Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
title_full Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
title_fullStr Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
title_full_unstemmed Unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (MELAS)
title_sort unilateral cortical thickening and hyper-intensity due to mitochondrial encephalopathy, lactic acidosis, and stroke like episodes (melas)
publisher Shahid Beheshti University of Medical Sciences
series International Clinical Neuroscience Journal
issn 2383-1871
2383-2096
publishDate 2014-04-01
description Patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) present with recurrent and partially reversible neurological deficits. Lesions of MELAS classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. These lesions mimic infarction. Here, we reported a case of MELAS with rare neuroimaging finding of hemispheric cortical thickening on T2/FLAIR images with intracortical nodular gadolinium enhancement; then we discussed the clinical and radiological differential diagnoses of it.
url http://journals.sbmu.ac.ir/Neuroscience/article/download/6754/pdf_4
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AT babakbakhshayesh unilateralcorticalthickeningandhyperintensityduetomitochondrialencephalopathylacticacidosisandstrokelikeepisodesmelas
AT nazaninrahmana unilateralcorticalthickeningandhyperintensityduetomitochondrialencephalopathylacticacidosisandstrokelikeepisodesmelas
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