Salvia miltiorrhiza Induces Tonic Contraction of the Lower Esophageal Sphincter in Rats via Activation of Extracellular Ca2+ Influx

Salvia miltiorrhiza Induces Tonic Contraction of the Lower Esophageal Sphincter in Rats via Activation of Extracellular Ca2+ Influx

Up to 40% of patients with gastroesophageal reflux disease (GERD) suffer from proton pump inhibitor refractory GERD but clinically the medications to strengthen the lower esophageal sphincter (LES) to avoid irritating reflux are few in number. This study aimed to examine whether Salvia miltiorrhiza...

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Bibliographic Details
Main Authors: Ching-Chung Tsai, Li-Ching Chang, Shih-Che Huang, Shu-Leei Tey, Wen-Li Hsu, Yu-Tsun Su, Ching-Wen Liu, Tong-Rong Tsai
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molecules
Subjects:
Salvia miltiorrhiza
tonic contraction
lower esophageal sphincter
Online Access:http://www.mdpi.com/1420-3049/20/8/14504

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