Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE

Abstract Widespread antibiotic resistance, especially of Gram-negative bacteria, has become a severe concern for human health. Tripartite efflux pumps are one of the major contributors to resistance in Gram-negative pathogens, by efficiently expelling a broad spectrum of antibiotics from the organis...

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Bibliographic Details
Main Authors: Giulia Tamburrino, Salomé Llabrés, Owen N. Vickery, Samantha J. Pitt, Ulrich Zachariae
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-16995-x