GST M1-T1 null allele frequency patterns in geographically assorted human populations: a phylogenetic approach.

Genetic diversity in drug metabolism and disposition is mainly considered as the outcome of the inter-individual genetic variation in polymorphism of drug-xenobiotic metabolizing enzyme (XME). Among the XMEs, glutathione-S-transferases (GST) gene loci are an important candidate for the investigation...

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Bibliographic Details
Main Authors: Senthilkumar Pitchalu Kasthurinaidu, Thirumurugan Ramasamy, Jayachitra Ayyavoo, Dhvani Kirtikumar Dave, Divya Anantray Adroja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395045?pdf=render