Senescence induction; a possible cancer therapy

<p>Abstract</p> <p>Cellular immortalization is a crucial step during the development of human cancer. Primary mammalian cells reach replicative exhaustion after several passages <it>in vitro</it>, a process called replicative senescence. During such a state of permanent...

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Bibliographic Details
Main Authors: Kondoh Hiroshi, Artero-Castro Ana, LLeonart Matilde E
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/3

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