Senescence induction; a possible cancer therapy
<p>Abstract</p> <p>Cellular immortalization is a crucial step during the development of human cancer. Primary mammalian cells reach replicative exhaustion after several passages <it>in vitro</it>, a process called replicative senescence. During such a state of permanent...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-01-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/8/1/3 |