Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer’s disease

Diurnal and seasonal rhythms modulate brain function, but we do not know the genomic basis for these rhythms. Here, Limet al. show diurnal and seasonal rhythms of gene expression in the human brain, their relationship to histone acetylation and DNA methylation, and their disruption in Alzheimer’s di...

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Bibliographic Details
Main Authors: Andrew S. P. Lim, Hans-Ulrich Klein, Lei Yu, Lori B. Chibnik, Sanam Ali, Jishu Xu, David A. Bennett, Philip L. De Jager
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14931