Blockade of Radiation-induced EGFR Nuclear Transport Enhances Radiosensitivity of Human Cervical Cancer

Blockade of Radiation-induced EGFR Nuclear Transport Enhances Radiosensitivity of Human Cervical Cancer

Objective To investigate whether the inhibition of EGFR nuclear transport could reduce the radioresistance of human cervical cancer cells. Methods Human cervical cancer CaSki and HeLa cells were exposed to radiation treated with or without Thr654 inhibitory peptide, cetuximab and gefitinib. The expr...

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Bibliographic Details
Main Authors: LI Lu, HUANG Jianming, FENG Mei, QI Yunxiang, MA Shiqi, TAN Mingyu, LANG Jinyi
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2020-01-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
cervical cancer
egfr
dna-pk
radiation therapy
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0807.htm

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