Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department.

Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department.

<h4>Objective</h4>To achieve an optimal effect in patients with sepsis at the emergency department (ED), the gentamicin peak-concentration should be sufficiently high (i.e. peak-concentration/MIC ≥8-10). ICU patients with sepsis often need higher gentamicin doses to achieve sufficiently...

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Bibliographic Details
Main Authors: Maarten Cobussen, Patricia M Stassen, Dirk Posthouwer, Frank H van Tiel, Paul H M Savelkoul, Thomas Havenith, Michiel B Haeseker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210012

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