Effects of Acanthopanax senticosus on Brain Injury Induced by Simulated Spatial Radiation in Mouse Model Based on Pharmacokinetics and Comparative Proteomics

Effects of Acanthopanax senticosus on Brain Injury Induced by Simulated Spatial Radiation in Mouse Model Based on Pharmacokinetics and Comparative Proteomics

The active compounds in Acanthopanax senticosus (AS) have different pharmacokinetic characteristics in mouse models. Cmax and AUC of Acanthopanax senticosus polysaccharides (ASPS) were significantly reduced in radiation-injured mice, suggesting that the blood flow of mouse was blocked or slowed, due...

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Bibliographic Details
Main Authors: Yingyu Zhou, Cuilin Cheng, Denis Baranenko, Jiaping Wang, Yongzhi Li, Weihong Lu
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
Acanthopanax senticosus (AS)
brain injury
pharmacokinetic
proteomics
Online Access:http://www.mdpi.com/1422-0067/19/1/159

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