The first organocatalytic carbonyl-ene reaction: isomerisation-free C-C bond formations catalysed by H-bonding thio-ureas

Intramolecular carbonyl ene reactions of highly activated enophiles can be catalysed by H-bonding thio-ureas to give tertiary alcohols in high yields without extensive isomerisation side products. An asymmetric variant of this reaction was realised using a chiral thiourea but was limited by low enan...

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Bibliographic Details
Main Authors: Matthew L. Clarke, Charlotte E. S. Jones, Marcia B. France
Format: Article
Language:English
Published: Beilstein-Institut 2007-09-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-3-24

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