Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer
The progression from biliary tract intraepithelial neoplasia (BilIN) to gallbladder carcinoma (GBC) remains unclear. Here the authors use genomics to analyze coexisting GBC lesions, low-grade and high-grade BilINs, revealing two distinct evolutionary paths for GBC development.
Bibliographic Details
| Main Authors: |
Jianzhen Lin,
Xinxin Peng,
Kun Dong,
Junyu Long,
Xuejiao Guo,
Hongyue Li,
Yi Bai,
Xu Yang,
Dongxu Wang,
Xin Lu,
Yilei Mao,
Xinting Sang,
Xuwo Ji,
Haitao Zhao,
Han Liang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-25012-9
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