Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)-presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid organ and bone marrow transplantation. One of the...

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Bibliographic Details
Main Authors: Anja Ten Brinke, Natalia Marek-Trzonkowska, Maria J. Mansilla, Annelies W. Turksma, Karolina Piekarska, Dorota Iwaszkiewicz-Grześ, Laura Passerini, Grazia Locafaro, Joan Puñet-Ortiz, S. Marieke van Ham, Maria P. Hernandez-Fuentes, Eva M. Martínez-Cáceres, Silvia Gregori
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
tolerance
monitoring
proliferation
antigen-specific
T cells
transplantation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01870/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01870/full

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