Anomalous Solubility Behavior of Several Acidic Drugs
The “anomalous solubility behavior at higher pH values” of several acidic drugs originally studied by Higuchi et al. in 1953 [1], but hitherto not fully rationalized, has been re-analyzed using a novel solubility-pH analysis computer program, pDISOL-XTM. The program internally derives implicit solu...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2014-04-01
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| Series: | ADMET and DMPK |
| Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/30 |