Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

Abstract Background Werner syndrome is a progeroid disorder characterized by premature age-related phenotypes. Although it is well established that autosomal recessive mutations in the WRN gene is responsible for Werner syndrome, the molecular alterations that lead to disease phenotype remain still...

Full description

Bibliographic Details
Main Authors: T. Guastafierro, M. G. Bacalini, A. Marcoccia, D. Gentilini, S. Pisoni, A. M. Di Blasio, A. Corsi, C. Franceschi, D. Raimondo, A. Spanò, P. Garagnani, F. Bondanini
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Clinical Epigenetics
Subjects:
Werner syndrome
DNA methylation
Systemic sclerosis
Online Access:http://link.springer.com/article/10.1186/s13148-017-0389-4

Similar Items

Similar Items