Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

Abstract Background Werner syndrome is a progeroid disorder characterized by premature age-related phenotypes. Although it is well established that autosomal recessive mutations in the WRN gene is responsible for Werner syndrome, the molecular alterations that lead to disease phenotype remain still...

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Bibliographic Details
Main Authors: T. Guastafierro, M. G. Bacalini, A. Marcoccia, D. Gentilini, S. Pisoni, A. M. Di Blasio, A. Corsi, C. Franceschi, D. Raimondo, A. Spanò, P. Garagnani, F. Bondanini
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Clinical Epigenetics
Subjects:
Werner syndrome
DNA methylation
Systemic sclerosis
Online Access:http://link.springer.com/article/10.1186/s13148-017-0389-4

Internet

http://link.springer.com/article/10.1186/s13148-017-0389-4

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