Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings
Ceruminous adenomas are benign tumors that are rare in humans and present with a nonspecific symptomatology. The treatment of choice is surgical excision. We present an 87-year-old woman who presented with a reddish, tender, round, soft mass of the outer third of the inferior wall of the left extern...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/359627 |
id |
doaj-14755b9141cb4f63b59af1a6c803e252 |
---|---|
record_format |
Article |
spelling |
doaj-14755b9141cb4f63b59af1a6c803e2522020-11-25T00:00:50ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/359627359627Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic FindingsGeorge Psillas0Argyrios Krommydas1Georgia Karayannopoulou2Kyriakos Chatzopoulos3Jean Kanitakis4Konstantinos Markou51st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, GreeceDepartment of Pathology, Aristotle University of Thessaloniki, School of Medicine, 541 24 Thessaloniki, GreeceDepartment of Pathology, Aristotle University of Thessaloniki, School of Medicine, 541 24 Thessaloniki, GreeceDepartment of Dermatology, Ed. Herriot Hospital Group, Lyon, France1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, GreeceCeruminous adenomas are benign tumors that are rare in humans and present with a nonspecific symptomatology. The treatment of choice is surgical excision. We present an 87-year-old woman who presented with a reddish, tender, round, soft mass of the outer third of the inferior wall of the left external auditory canal, discharging a yellowish fluid upon pressure. Coincidentally, due to her poor general condition, this patient also showed symptoms consistent with chronic otitis media, parotitis, and cervical lymphadenopathy, such as otorrhea, through a ruptured tympanic membrane and swelling of the parotid gland and cervical lymph nodes. The external auditory canal lesion was surgically excised under general anesthesia, utilizing a transmeatal approach. The pathological diagnosis was ceruminous gland adenoma. The tumor was made of tubular and cystic structures and embedded in a fibrous, focally hyalinized stroma. Immunohistochemistry confirmed the presence of two distinct cell populations. The luminal cells expressed keratin 7, while peripheral (basal) cells expressed keratins 5/6, S100 protein, and p63. The apocrine gland-related antigen GCDFP-15 was focally expressed by tumor cells. The postoperative course was uneventful and at the 2-year follow-up no recurrence of the ceruminous adenoma was noted.http://dx.doi.org/10.1155/2015/359627 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
George Psillas Argyrios Krommydas Georgia Karayannopoulou Kyriakos Chatzopoulos Jean Kanitakis Konstantinos Markou |
spellingShingle |
George Psillas Argyrios Krommydas Georgia Karayannopoulou Kyriakos Chatzopoulos Jean Kanitakis Konstantinos Markou Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings Case Reports in Medicine |
author_facet |
George Psillas Argyrios Krommydas Georgia Karayannopoulou Kyriakos Chatzopoulos Jean Kanitakis Konstantinos Markou |
author_sort |
George Psillas |
title |
Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings |
title_short |
Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings |
title_full |
Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings |
title_fullStr |
Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings |
title_full_unstemmed |
Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings |
title_sort |
ceruminous adenoma of the external auditory canal: a case report with imaging and pathologic findings |
publisher |
Hindawi Limited |
series |
Case Reports in Medicine |
issn |
1687-9627 1687-9635 |
publishDate |
2015-01-01 |
description |
Ceruminous adenomas are benign tumors that are rare in humans and present with a nonspecific symptomatology. The treatment of choice is surgical excision. We present an 87-year-old woman who presented with a reddish, tender, round, soft mass of the outer third of the inferior wall of the left external auditory canal, discharging a yellowish fluid upon pressure. Coincidentally, due to her poor general condition, this patient also showed symptoms consistent with chronic otitis media, parotitis, and cervical lymphadenopathy, such as otorrhea, through a ruptured tympanic membrane and swelling of the parotid gland and cervical lymph nodes. The external auditory canal lesion was surgically excised under general anesthesia, utilizing a transmeatal approach. The pathological diagnosis was ceruminous gland adenoma. The tumor was made of tubular and cystic structures and embedded in a fibrous, focally hyalinized stroma. Immunohistochemistry confirmed the presence of two distinct cell populations. The luminal cells expressed keratin 7, while peripheral (basal) cells expressed keratins 5/6, S100 protein, and p63. The apocrine gland-related antigen GCDFP-15 was focally expressed by tumor cells. The postoperative course was uneventful and at the 2-year follow-up no recurrence of the ceruminous adenoma was noted. |
url |
http://dx.doi.org/10.1155/2015/359627 |
work_keys_str_mv |
AT georgepsillas ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings AT argyrioskrommydas ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings AT georgiakarayannopoulou ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings AT kyriakoschatzopoulos ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings AT jeankanitakis ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings AT konstantinosmarkou ceruminousadenomaoftheexternalauditorycanalacasereportwithimagingandpathologicfindings |
_version_ |
1725443138385870848 |