Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans

Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans

The data presented here are related to the research article entitled “Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans” (Shroff et al., 2018) [1]. The cited research article describes the role of au...

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Main Authors: Ankit Shroff, Roicy Sequeira, Vainav Patel, K.V.R. Reddy
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918302075
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spelling doaj-146f3da2e5784f4f85321846824d5e372020-11-25T02:19:00ZengElsevierData in Brief2352-34092018-06-0118432440Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicansAnkit Shroff0Roicy Sequeira1Vainav Patel2K.V.R. Reddy3Division of Molecular Immunology & Microbiology (MIM), National Institute for Research in Reproductive Health (NIRRH), J. M. Street, Parel, Mumbai 400012, IndiaDivision of Molecular Immunology & Microbiology (MIM), National Institute for Research in Reproductive Health (NIRRH), J. M. Street, Parel, Mumbai 400012, IndiaDepartment of Biochemistry & Virology, National Institute for Research in Reproductive Health (NIRRH), J. M. Street, Parel, Mumbai 400012, IndiaDivision of Molecular Immunology & Microbiology (MIM), National Institute for Research in Reproductive Health (NIRRH), J. M. Street, Parel, Mumbai 400012, India; Corresponding author.The data presented here are related to the research article entitled “Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans” (Shroff et al., 2018) [1]. The cited research article describes the role of autophagy in host immune response against C. albicans infection of mice vagina. In this data report wild-type C57BL/6 mice were infected intravaginally with C. albicans. Vaginal cells were analyzed for the expression of autophagy marker genes LC3 & ATG5 and lysosome marker LAMP1 at the transcript and protein level. Vaginal lavages were also obtained from these infected mice. The levels of pro-inflammatory and T-helper cell related cytokines were determined in these lavages. Keywords: Autophagy markers, ATG5, Vaginal infection, Candida albicans, Cytokineshttp://www.sciencedirect.com/science/article/pii/S2352340918302075
collection DOAJ
language English
format Article
sources DOAJ
author Ankit Shroff
Roicy Sequeira
Vainav Patel
K.V.R. Reddy
spellingShingle Ankit Shroff
Roicy Sequeira
Vainav Patel
K.V.R. Reddy
Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
Data in Brief
author_facet Ankit Shroff
Roicy Sequeira
Vainav Patel
K.V.R. Reddy
author_sort Ankit Shroff
title Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
title_short Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
title_full Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
title_fullStr Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
title_full_unstemmed Data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of Candida albicans
title_sort data on autophagy markers and anti-candida cytokines expression in mice in response to vaginal infection of candida albicans
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2018-06-01
description The data presented here are related to the research article entitled “Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans” (Shroff et al., 2018) [1]. The cited research article describes the role of autophagy in host immune response against C. albicans infection of mice vagina. In this data report wild-type C57BL/6 mice were infected intravaginally with C. albicans. Vaginal cells were analyzed for the expression of autophagy marker genes LC3 & ATG5 and lysosome marker LAMP1 at the transcript and protein level. Vaginal lavages were also obtained from these infected mice. The levels of pro-inflammatory and T-helper cell related cytokines were determined in these lavages. Keywords: Autophagy markers, ATG5, Vaginal infection, Candida albicans, Cytokines
url http://www.sciencedirect.com/science/article/pii/S2352340918302075
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