Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.

Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.

The signaling of Toll-like receptors (TLRs) induces host defense against microbial invasion. Protein posttranslational modifications dynamically shape the strength and duration of the signaling pathways. It is intriguing to explore whether de-SUMOylation could modulate the TLR signaling. Here we ide...

Full description

Bibliographic Details
Main Authors: Xing Liu, Wei Chen, Qiang Wang, Li Li, Chen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3694847?pdf=render

Similar Items

Similar Items