Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience

Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience

Mast cell activation syndrome (MCAS) is a disorder in which patients experience symptoms and signs attributable to inappropriate mast cell activation and mediator release. Multiorgan involvement in patients can result in significant morbidity and possible mortality. Limited literature exists regardi...

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Main Authors: Sangeeta Kumaraswami, Gabriel Farkas
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2018/8920921
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spelling doaj-1463abd521a04869a59779a73bab74722020-11-24T21:56:49ZengHindawi LimitedCase Reports in Anesthesiology2090-63822090-63902018-01-01201810.1155/2018/89209218920921Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s ExperienceSangeeta Kumaraswami0Gabriel Farkas1Department of Anesthesiology, New York Medical College at Westchester Medical Center, Valhalla, NY, USADepartment of Anesthesiology, New York Medical College at Westchester Medical Center, Valhalla, NY, USAMast cell activation syndrome (MCAS) is a disorder in which patients experience symptoms and signs attributable to inappropriate mast cell activation and mediator release. Multiorgan involvement in patients can result in significant morbidity and possible mortality. Limited literature exists regarding anesthetic management of patients with MCAS. We report a case of vaginal delivery with neuraxial labor analgesia in a parturient with this condition and highlight the importance of multidisciplinary planning for uneventful outcomes. Stress can trigger life-threatening symptoms, and counseling is important to allay patients’ fears. Optimum medical control, adequate premedication, avoidance of triggers, and preparedness to treat serious mediator effects are key. We review MCAS and discuss anesthetic considerations for patients with this mast cell disorder.http://dx.doi.org/10.1155/2018/8920921
collection DOAJ
language English
format Article
sources DOAJ
author Sangeeta Kumaraswami
Gabriel Farkas
spellingShingle Sangeeta Kumaraswami
Gabriel Farkas
Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
Case Reports in Anesthesiology
author_facet Sangeeta Kumaraswami
Gabriel Farkas
author_sort Sangeeta Kumaraswami
title Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
title_short Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
title_full Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
title_fullStr Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
title_full_unstemmed Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience
title_sort management of a parturient with mast cell activation syndrome: an anesthesiologist’s experience
publisher Hindawi Limited
series Case Reports in Anesthesiology
issn 2090-6382
2090-6390
publishDate 2018-01-01
description Mast cell activation syndrome (MCAS) is a disorder in which patients experience symptoms and signs attributable to inappropriate mast cell activation and mediator release. Multiorgan involvement in patients can result in significant morbidity and possible mortality. Limited literature exists regarding anesthetic management of patients with MCAS. We report a case of vaginal delivery with neuraxial labor analgesia in a parturient with this condition and highlight the importance of multidisciplinary planning for uneventful outcomes. Stress can trigger life-threatening symptoms, and counseling is important to allay patients’ fears. Optimum medical control, adequate premedication, avoidance of triggers, and preparedness to treat serious mediator effects are key. We review MCAS and discuss anesthetic considerations for patients with this mast cell disorder.
url http://dx.doi.org/10.1155/2018/8920921
work_keys_str_mv AT sangeetakumaraswami managementofaparturientwithmastcellactivationsyndromeananesthesiologistsexperience
AT gabrielfarkas managementofaparturientwithmastcellactivationsyndromeananesthesiologistsexperience
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