Caldaret, an Intracellular Ca2+ Handling Modulator, Limits Infarct Size of Reperfused Canine Heart
The cardioprotective effect of caldaret, a novel intracellular Ca2+ handling modulator that acts through reverse-mode Na+/Ca2+ exchanger inhibition and potential sarcoplasmic reticulum (SR) Ca2+ uptake enhancement, against reperfusion injury was investigated. We employed a canine model of myocardial...
Main Authors: | Hisashi Kawasumi, Naoya Satoh, Yoshimi Kitada |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319343282 |
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