Caldaret, an Intracellular Ca2+ Handling Modulator, Limits Infarct Size of Reperfused Canine Heart

The cardioprotective effect of caldaret, a novel intracellular Ca2+ handling modulator that acts through reverse-mode Na+/Ca2+ exchanger inhibition and potential sarcoplasmic reticulum (SR) Ca2+ uptake enhancement, against reperfusion injury was investigated. We employed a canine model of myocardial...

Full description

Bibliographic Details
Main Authors: Hisashi Kawasumi, Naoya Satoh, Yoshimi Kitada
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319343282