West Nile virus experimental evolution in vivo and the trade-off hypothesis.

In nature, arthropod-borne viruses (arboviruses) perpetuate through alternating replication in vertebrate and invertebrate hosts. The trade-off hypothesis proposes that these viruses maintain adequate replicative fitness in two disparate hosts in exchange for superior fitness in one host. Releasing...

Full description

Bibliographic Details
Main Authors: Eleanor R Deardorff, Kelly A Fitzpatrick, Greta V S Jerzak, Pei-Yong Shi, Laura D Kramer, Gregory D Ebel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3213084?pdf=render