Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?

Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?

Abstract Bronchial asthma (BA) is a chronic inflammatory disease with a marked heterogeneity in pathophysiology and etiology. The heterogeneity of BA may be related to the inducing mechanism(s) (allergic vs non-allergic), the histopathological background (eosinophilic vs non-eosinophilic), and the c...

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Bibliographic Details
Main Authors: Andrea Matucci, Alessandra Vultaggio, Enrico Maggi, Ismail Kasujee
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Respiratory Research
Subjects:
Immunoglobulin E
IgE
Eosinophil
Interleukin 5
IL-5
Asthma pathogenesis; anti-IgE
Online Access:http://link.springer.com/article/10.1186/s12931-018-0813-0

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