| Summary: | The paper shows the results of a comparative assessment of the seasonal and age patterns of autarcesis in Orenburg goats. Intact healthy goats were studied as control groups: 1st experimental group - breeding male goats (n=10), 2nd group – breeding female goats (n=10), 3rd experimental group - gimmer hogs (n=10), and 4th experimental group - young wethers (n = 10). The autarcesis is marked by humoral factors, for example, indicators of the bactericidal activity of the blood serum, lysozyme activity, and beta-lytic activity (thrombodefensin activity). The investigations have shown that the maximum values of the bactericidal activity of the blood serum were found in the autumn and winter times in the experimental groups. Their values were 73,75±1,07 %, 78,28±0,85 %, 65,89±1,16 %, and 71,16±0,71 %, respectively. The minimum values are determined in spring and summer. A similar pattern was found in the study of beta-lytic activity in the autumn-winter time, but the highest values were observed in the animals of the experimental group of 9.43±0.12% and 9.86±0.15 %, respectively. The decrease in the bactericidal activity of the blood and the beta-lytic activity in the summer time was recompensed by the values of lysozyme activity. Thus, the highest immunological indices were found in summer time. The highest values of white blood cells were found in the blood of the gimmer hogs and young wethers. Meanwhile, the studied indicators did not overstep the limits of the physiological standard. The data obtained are suggested to be used in breeding work for the reproduction of animals with a high level of autarcesis.
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