UV radiation recruits CD4+GATA3+ and CD8+GATA3+ T cells while altering the lipid microenvironment following inflammatory resolution in human skin in vivo

UV radiation recruits CD4+GATA3+ and CD8+GATA3+ T cells while altering the lipid microenvironment following inflammatory resolution in human skin in vivo

Abstract Objectives Solar ultraviolet radiation (UVR) has major adverse effects on human health. While the mechanisms responsible for induction of UVR‐induced inflammation are well‐documented, the mediation of its resolution and longer‐term adaptive homeostasis is unknown. Therefore, we examined the...

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Bibliographic Details
Main Authors: Nathan J Hawkshaw, Suzanne M Pilkington, Sharon A Murphy, Norah Al‐Gazaq, Mark D Farrar, Rachel EB Watson, Anna Nicolaou, Lesley E Rhodes
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
inflammation
immunosuppression
lipidomics
resolution
T cells
ultraviolet radiation
Online Access:https://doi.org/10.1002/cti2.1104

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