Axonal outgrowth is associated with increased ERK 1/2 activation but decreased caspase 3 linked cell death in Schwann cells after immediate nerve repair in rats

<p>Abstract</p> <p>Background</p> <p>Extracellular-signal regulated kinase (ERK1/2) is activated by nerve damage and its activation precedes survival and proliferation of Schwann cells. In contrast, activation of caspase 3, a cysteine protease, is considered as a marker...

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Bibliographic Details
Main Authors: Kanje Martin, Tsuda Yoshifumi, Dahlin Lars B
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/12

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