Axonal outgrowth is associated with increased ERK 1/2 activation but decreased caspase 3 linked cell death in Schwann cells after immediate nerve repair in rats
<p>Abstract</p> <p>Background</p> <p>Extracellular-signal regulated kinase (ERK1/2) is activated by nerve damage and its activation precedes survival and proliferation of Schwann cells. In contrast, activation of caspase 3, a cysteine protease, is considered as a marker...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-01-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/12/12 |