C3G Protein, a New Player in Glioblastoma

C3G Protein, a New Player in Glioblastoma

C3G (RAPGEF1) is a guanine nucleotide exchange factor (GEF) for GTPases from the Ras superfamily, mainly Rap1, although it also acts through GEF-independent mechanisms. C3G regulates several cellular functions. It is expressed at relatively high levels in specific brain areas, playing important role...

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Bibliographic Details
Main Authors: Sara Manzano, Alvaro Gutierrez-Uzquiza, Paloma Bragado, Angel M Cuesta, Carmen Guerrero, Almudena Porras
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
C3G
glioblastoma
Rap
Online Access:https://www.mdpi.com/1422-0067/22/18/10018

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