Neonatal Oxytocin Treatment Ameliorates Autistic-Like Behaviors and Oxytocin Deficiency in Valproic Acid-Induced Rat Model of Autism

Neonatal Oxytocin Treatment Ameliorates Autistic-Like Behaviors and Oxytocin Deficiency in Valproic Acid-Induced Rat Model of Autism

Autism spectrum disorder (ASD) is characterized by impaired social communication and repetitive/stereotyped behaviors. The neuropeptide oxytocin (OXT) plays a critical role in regulating social behaviors in the central nervous system, as indicated in both human and animal studies. We hypothesized th...

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Bibliographic Details
Main Authors: Yu-Chuan Dai, Hong-Feng Zhang, Michael Schön, Tobias M. Böckers, Song-Ping Han, Ji-Sheng Han, Rong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
autism spectrum disorder
social behavior defect
repetitive behavior
exogenous supplement
oxytocin therapy
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00355/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00355/full

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