Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants

Long non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in comp...

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Main Authors: Muhammad Waseem, Yuanlong Liu, Rui Xia
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/1/86
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spelling doaj-141ee25983124d1285535c3be3ec9a8b2020-12-24T00:06:14ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-12-0122868610.3390/ijms22010086Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in PlantsMuhammad Waseem0Yuanlong Liu1Rui Xia2State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaLong non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in computational and experimental approaches have identified numerous lncRNAs in plants. lncRNAs have been found to act as prime mediators in plant growth, development, and tolerance to stresses. This review summarizes the current research status of lncRNAs in planta, their classification based on genomic context, their mechanism of action, and specific bioinformatics tools and resources for their identification and characterization. Our overarching goal is to summarize recent progress on understanding the regulatory role of lncRNAs in plant developmental processes such as flowering time, reproductive growth, and abiotic stresses. We also review the role of lncRNA in nutrient stress and the ability to improve biotic stress tolerance in plants. Given the pivotal role of lncRNAs in various biological processes, their functional characterization in agriculturally essential crop plants is crucial for bridging the gap between phenotype and genotype.https://www.mdpi.com/1422-0067/22/1/86lncRNAsdark matterregulatordatabaseepigeneticstolerance
collection DOAJ
language English
format Article
sources DOAJ
author Muhammad Waseem
Yuanlong Liu
Rui Xia
spellingShingle Muhammad Waseem
Yuanlong Liu
Rui Xia
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
International Journal of Molecular Sciences
lncRNAs
dark matter
regulator
database
epigenetics
tolerance
author_facet Muhammad Waseem
Yuanlong Liu
Rui Xia
author_sort Muhammad Waseem
title Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
title_short Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
title_full Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
title_fullStr Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
title_full_unstemmed Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
title_sort long non-coding rnas, the dark matter: an emerging regulatory component in plants
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1661-6596
1422-0067
publishDate 2021-12-01
description Long non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in computational and experimental approaches have identified numerous lncRNAs in plants. lncRNAs have been found to act as prime mediators in plant growth, development, and tolerance to stresses. This review summarizes the current research status of lncRNAs in planta, their classification based on genomic context, their mechanism of action, and specific bioinformatics tools and resources for their identification and characterization. Our overarching goal is to summarize recent progress on understanding the regulatory role of lncRNAs in plant developmental processes such as flowering time, reproductive growth, and abiotic stresses. We also review the role of lncRNA in nutrient stress and the ability to improve biotic stress tolerance in plants. Given the pivotal role of lncRNAs in various biological processes, their functional characterization in agriculturally essential crop plants is crucial for bridging the gap between phenotype and genotype.
topic lncRNAs
dark matter
regulator
database
epigenetics
tolerance
url https://www.mdpi.com/1422-0067/22/1/86
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AT yuanlongliu longnoncodingrnasthedarkmatteranemergingregulatorycomponentinplants
AT ruixia longnoncodingrnasthedarkmatteranemergingregulatorycomponentinplants
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