Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants
Long non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in comp...
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doaj-141ee25983124d1285535c3be3ec9a8b2020-12-24T00:06:14ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-12-0122868610.3390/ijms22010086Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in PlantsMuhammad Waseem0Yuanlong Liu1Rui Xia2State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, Guangdong 510640, ChinaLong non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in computational and experimental approaches have identified numerous lncRNAs in plants. lncRNAs have been found to act as prime mediators in plant growth, development, and tolerance to stresses. This review summarizes the current research status of lncRNAs in planta, their classification based on genomic context, their mechanism of action, and specific bioinformatics tools and resources for their identification and characterization. Our overarching goal is to summarize recent progress on understanding the regulatory role of lncRNAs in plant developmental processes such as flowering time, reproductive growth, and abiotic stresses. We also review the role of lncRNA in nutrient stress and the ability to improve biotic stress tolerance in plants. Given the pivotal role of lncRNAs in various biological processes, their functional characterization in agriculturally essential crop plants is crucial for bridging the gap between phenotype and genotype.https://www.mdpi.com/1422-0067/22/1/86lncRNAsdark matterregulatordatabaseepigeneticstolerance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Muhammad Waseem Yuanlong Liu Rui Xia |
spellingShingle |
Muhammad Waseem Yuanlong Liu Rui Xia Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants International Journal of Molecular Sciences lncRNAs dark matter regulator database epigenetics tolerance |
author_facet |
Muhammad Waseem Yuanlong Liu Rui Xia |
author_sort |
Muhammad Waseem |
title |
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants |
title_short |
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants |
title_full |
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants |
title_fullStr |
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants |
title_full_unstemmed |
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants |
title_sort |
long non-coding rnas, the dark matter: an emerging regulatory component in plants |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1661-6596 1422-0067 |
publishDate |
2021-12-01 |
description |
Long non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in computational and experimental approaches have identified numerous lncRNAs in plants. lncRNAs have been found to act as prime mediators in plant growth, development, and tolerance to stresses. This review summarizes the current research status of lncRNAs in planta, their classification based on genomic context, their mechanism of action, and specific bioinformatics tools and resources for their identification and characterization. Our overarching goal is to summarize recent progress on understanding the regulatory role of lncRNAs in plant developmental processes such as flowering time, reproductive growth, and abiotic stresses. We also review the role of lncRNA in nutrient stress and the ability to improve biotic stress tolerance in plants. Given the pivotal role of lncRNAs in various biological processes, their functional characterization in agriculturally essential crop plants is crucial for bridging the gap between phenotype and genotype. |
topic |
lncRNAs dark matter regulator database epigenetics tolerance |
url |
https://www.mdpi.com/1422-0067/22/1/86 |
work_keys_str_mv |
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1724372173691289600 |