A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)

A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)

Diethylcyanophosphonate (DCNP) is a simulant of Tabun (GA) which is an extremely toxic chemical substance and is used as a chemical warfare (CW) nerve agent. Due to its toxic properties, monitoring methods have been constantly come under the spotlight. What we are proposing within this report is a n...

Full description

Bibliographic Details
Main Authors: Yuna Jung, Dokyoung Kim
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Materials
Subjects:
molecular probe
reaction-based probe
diethylcyanophosphonate
nerve agent
real-time detection
Online Access:https://www.mdpi.com/1996-1944/12/18/2943
id doaj-140ec890d27844559c326d6fc478db2c
record_format Article
spelling doaj-140ec890d27844559c326d6fc478db2c2020-11-25T01:25:44ZengMDPI AGMaterials1996-19442019-09-011218294310.3390/ma12182943ma12182943A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)Yuna Jung0Dokyoung Kim1Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, KoreaDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, KoreaDiethylcyanophosphonate (DCNP) is a simulant of Tabun (GA) which is an extremely toxic chemical substance and is used as a chemical warfare (CW) nerve agent. Due to its toxic properties, monitoring methods have been constantly come under the spotlight. What we are proposing within this report is a next-generation fluorescent probe, <b>DMHN1</b>, which allows DCNP to become fully traceable in a sensitive, selective, and responsive manner. This is the first fluorescent turn-on probe within the dipolar naphthalene platform induced by ESIPT (excited state intramolecular proton transfer) suppression that allows us to sense DCNP without any disturbance by other similar G-series chemical weapons. The successful demonstrations of practical applications, such as in vitro analysis, soil analysis, and the development of an on-site real-time prototype sensing kit, encourage further applications in a variety of fields.https://www.mdpi.com/1996-1944/12/18/2943molecular probereaction-based probediethylcyanophosphonatenerve agentreal-time detection
collection DOAJ
language English
format Article
sources DOAJ
author Yuna Jung
Dokyoung Kim
spellingShingle Yuna Jung
Dokyoung Kim
A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
Materials
molecular probe
reaction-based probe
diethylcyanophosphonate
nerve agent
real-time detection
author_facet Yuna Jung
Dokyoung Kim
author_sort Yuna Jung
title A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
title_short A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
title_full A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
title_fullStr A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
title_full_unstemmed A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant)
title_sort selective fluorescence turn-on probe for the detection of dcnp (nerve agent tabun simulant)
publisher MDPI AG
series Materials
issn 1996-1944
publishDate 2019-09-01
description Diethylcyanophosphonate (DCNP) is a simulant of Tabun (GA) which is an extremely toxic chemical substance and is used as a chemical warfare (CW) nerve agent. Due to its toxic properties, monitoring methods have been constantly come under the spotlight. What we are proposing within this report is a next-generation fluorescent probe, <b>DMHN1</b>, which allows DCNP to become fully traceable in a sensitive, selective, and responsive manner. This is the first fluorescent turn-on probe within the dipolar naphthalene platform induced by ESIPT (excited state intramolecular proton transfer) suppression that allows us to sense DCNP without any disturbance by other similar G-series chemical weapons. The successful demonstrations of practical applications, such as in vitro analysis, soil analysis, and the development of an on-site real-time prototype sensing kit, encourage further applications in a variety of fields.
topic molecular probe
reaction-based probe
diethylcyanophosphonate
nerve agent
real-time detection
url https://www.mdpi.com/1996-1944/12/18/2943
work_keys_str_mv AT yunajung aselectivefluorescenceturnonprobeforthedetectionofdcnpnerveagenttabunsimulant
AT dokyoungkim aselectivefluorescenceturnonprobeforthedetectionofdcnpnerveagenttabunsimulant
AT yunajung selectivefluorescenceturnonprobeforthedetectionofdcnpnerveagenttabunsimulant
AT dokyoungkim selectivefluorescenceturnonprobeforthedetectionofdcnpnerveagenttabunsimulant
_version_ 1725112115545505792

Similar Items