Older adults lack SARS CoV-2 cross-reactive T lymphocytes directed to human coronaviruses OC43 and NL63

Older adults lack SARS CoV-2 cross-reactive T lymphocytes directed to human coronaviruses OC43 and NL63

Abstract Currently, infections with SARS-Coronavirus-2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, are responsible for substantial morbidity and mortality worldwide. Older adults subjects > 60 years of age account for > 95% of the over one million fatal cases reported to date....

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Main Authors: Giulietta Saletti, Thomas Gerlach, Janina M. Jansen, Antonia Molle, Husni Elbahesh, Martin Ludlow, Wentao Li, Berend-Jan Bosch, Albert D. M. E. Osterhaus, Guus F. Rimmelzwaan
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78506-9

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