Transcriptomic and Epigenetic Alterations in Dendritic Cells Correspond With Chronic Kidney Disease in Lupus Nephritis

Transcriptomic and Epigenetic Alterations in Dendritic Cells Correspond With Chronic Kidney Disease in Lupus Nephritis

Systemic lupus erythematosus (SLE) is a serious autoimmune disease with variety of organ manifestations. The most dreadful one, affecting the majority of SLE patients, is kidney manifestation—lupus nephritis (LN). Dendritic cells (DC) are believed to be one of the culprits of immune dysregulation in...

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Bibliographic Details
Main Authors: Anna Wardowska, Michał Komorniczak, Barbara Bułło-Piontecka, M. Alicja Dȩbska-Ślizień, Michał Pikuła
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
DNA methylation
histone modifications
interferon regulatory factors
chronic kidney disease
systemic lupus erythematosus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02026/full

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