Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastrointestinal (GI) tract and epithelia, the therapeut...

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Bibliographic Details
Main Authors: Quangang Zhu, Zhongjian Chen, Pijush Kumar Paul, Yi Lu, Wei Wu, Jianping Qi
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Proteins
Peptides
Oral delivery
Permeation enhancer
Enzyme inhibitor
Stability
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521001167

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http://www.sciencedirect.com/science/article/pii/S2211383521001167

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