Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics

Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics

<p>Abstract</p> <p>Background</p> <p>Aminoglycoside ototoxicity is one of the common health problems. Mitochondrial 12S rRNA mutations are one of the important causes of aminoglycoside ototoxicity. However, the incidences of 12S rRNA mutations associated with aminoglyco...

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Bibliographic Details
Main Authors: Zhou Jianjin, Yang Li, Zhang Chuqin, Li Ronghua, Zhu Yi, Gong Shasha, Zhang Ting, Peng Guanghua, Chen Bobei, Zheng Jing, Shen Zhisen, Cai Ting, Jin Lihua, Lu Jianxin, Guan Min-Xin
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/4

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