Impact of <i>CYP2C9</i> and <i>VKORC1</i> Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy

Impact of <i>CYP2C9</i> and <i>VKORC1</i> Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy

Warfarin is an oral anticoagulant frequently used in the treatment of different cardiovascular diseases. Genetic polymorphisms in the <i>CYP2C9</i> and <i>VKORC1</i> genes have produced variants with altered catalytic properties. A total of 212 cardiovascular patients were ge...

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Bibliographic Details
Main Authors: Laith N. AL-Eitan, Ayah Y. Almasri, Rame H. Khasawneh
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Genes
Subjects:
<i>CYP2C9</i>
<i>VKORC1</i>
warfarin
warfarin initiation phase of therapy
INR
pharmacogenetics study
Online Access:https://www.mdpi.com/2073-4425/9/12/578

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