Anti-Human Endoglin (hCD105) Immunotoxin—Containing Recombinant Single Chain Ribosome-Inactivating Protein Musarmin 1

Anti-Human Endoglin (hCD105) Immunotoxin—Containing Recombinant Single Chain Ribosome-Inactivating Protein Musarmin 1

Endoglin (CD105) is an accessory component of the TGF-β receptor complex, which is expressed in a number of tissues and over-expressed in the endothelial cells of tumor neovasculature. Targeting endoglin with immunotoxins containing type 2 ribosome-inactivating proteins has proved an effective tool...

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Bibliographic Details
Main Authors: Begoña Barriuso, Pilar Antolín, F. Javier Arias, Alessandra Girotti, Pilar Jiménez, Manuel Cordoba-Diaz, Damián Cordoba-Diaz, Tomás Girbés
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Toxins
Subjects:
recombinant musarmin
endoglin
CD105
44G4
anti-endoglin monoclonal antibody
anti-tumor therapy
cancer therapy
Online Access:http://www.mdpi.com/2072-6651/8/6/184

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