Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARγ Signaling

Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARγ Signaling

Background/Aims: Comparative gene identification-58 (CGI-58), an adipose triglyceride lipase (ATGL) coactivator, strongly promotes ATGL-mediated triglyceride (TG) catabolism. Beyond its function in promoting lipolysis, other features of CGI-58 have been proposed. Here, we investigated the role of CG...

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Bibliographic Details
Main Authors: Dan Yang, Haimei Chen, Xu Zeng, Ping Xie, Xincun Wang, Chang Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
CGI-58
PPARs
Inflammation
ROS
Mitochondrial dysfunction
Online Access:http://www.karger.com/Article/FullText/443027

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