Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and Suppresses Tumor Growth on Xenografts Tumor Animal Model

Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and Suppresses Tumor Growth on Xenografts Tumor Animal Model

Saponins are natural compounds and possess the most promising anti-cancer function. Here, a saponin gleditsia saponin C (GSC), extracted from gleditsiae fructus abnormalis, could induce apoptosis of lung tumor cell line A549 via caspase dependent cascade and this effect could be prevented by the cas...

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Bibliographic Details
Main Authors: Ye Cheng, Weidong He, Yongming He
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
natural product
gleditsia saponin C
apoptosis
lung cancer
drug development
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00988/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00988/full

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