The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to determine how an aggregate-forming protein common to several neurodegenerative disorders propagates throughout the brain. Many neurodegenerative conditions involve aggregates created by ‘prion-like’ pro...

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Bibliographic Details
Main Authors: Myungjin Jo, Shinrye Lee, Yu-Mi Jeon, Seyeon Kim, Younghwi Kwon, Hyung-Jun Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-00513-7