Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene Therapy
Oncolytic virus (OV) therapy utilizes replication-competent viruses to kill cancer cells, leaving non-malignant cells unharmed. With the first U.S. Food and Drug Administration-approved OV, dozens of clinical trials ongoing, and an abundance of translational research in the field, OV therapy is pois...
Main Authors: | Christian Bressy, Eric Hastie, Valery Z. Grdzelishvili |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-06-01
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Series: | Molecular Therapy: Oncolytics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770517300098 |
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