Embryonic stem cell microenvironment enhances proliferation of human retinal pigment epithelium cells by activating the PI3K signaling pathway

Embryonic stem cell microenvironment enhances proliferation of human retinal pigment epithelium cells by activating the PI3K signaling pathway

Abstract Background Retinal pigment epithelium (RPE) replacement has been proposed as an efficacious treatment for age-related macular degeneration (AMD), which is the primary cause of vision loss in the elderly worldwide. The embryonic stem cell (ESC) microenvironment has been demonstrated to enabl...

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Bibliographic Details
Main Authors: Jiahui Liu, Liu Yang, Xiaoran Wang, Shoubi Wang, Zheqian Huang, Chaoyang Li, Ying Liu, Yaqi Cheng, Chengxiu Liu, Zhichong Wang
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
Embryonic stem cell microenvironment
Proliferation
PI3K pathway
Regenerative medicine
Online Access:http://link.springer.com/article/10.1186/s13287-020-01923-0

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