Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells

Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells

Background/Aims: Chloroquine can induce an increase in the cellular uptake of glucose; however, the underlying mechanism is unclear. Methods: In this study, translocation of GLUT4 and intracellular Ca2+ changes were simultaneously observed by confocal microscope in L6 cells stably over-expressing IR...

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Bibliographic Details
Main Authors: Qi Zhou, Xinzhou Yang, Mingrui Xiong, Xiaolan Xu, Li Zhen, Weiwei Chen, Yan Wang, Jinhua Shen, Ping Zhao, Qing-Hua Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Chloroquine
Glucose uptake
GLUT4
Ca2+
Online Access:http://www.karger.com/Article/FullText/445562

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