FOXO3 Is Expressed in Ovarian Tissues and Acts as an Apoptosis Initiator in Granulosa Cells of Chickens
FOXO3, which encodes the transcription factor forkhead box O-3 (FoxO3), is a member of the FOXO subfamily of the forkhead box (FOX) family. FOXO3 can be negatively regulated by its phosphorylation by the PI3K/Akt signaling pathway and ultimately drives apoptosis when activated. In mammalian ovaries,...
Main Authors: | Can Cui, Shunshun Han, Huadong Yin, Bin Luo, Xiaoxu Shen, Fuling Yang, Zihao Liu, Qing Zhu, Diyan Li, Yan Wang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2019/6902906 |
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