Activated Ras alters lens and corneal development through induction of distinct downstream targets
<p>Abstract</p> <p>Background</p> <p>Mammalian Ras genes regulate diverse cellular processes including proliferation and differentiation and are frequently mutated in human cancers. Tumor development in response to Ras activation varies between different tissues and the...
Main Authors: | Reneker Lixing, Kuracha Murali R, Vaca Ryan, Siefker Ed, Zhang Yan, Burgess Daniel, Overbeek Paul A, Govindarajan Venkatesh |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | BMC Developmental Biology |
Online Access: | http://www.biomedcentral.com/1471-213X/10/13 |
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