INCIDENCE OF TUMOR CELLS PRESENCE ON HISTOPATHOLOGICAL SPECIMENTS MARGINS IN RELATION TO WIDENESS OF INTRAORAL CARCINOMAS EXCISION

• Main Authors: Dragan Mihailović, Zoran Pešić, Dragan Krasić
• Format: Article
• Language: English
• Published: University in Nis, Faculty of Medicine 2003-07-01
• Series: Acta Medica Medianae
• Subjects: carcinomas; intraoral; histopathological; margins
• Online Access: http://publisher.medfak.ni.ac.rs/2003-html/3-broj/INCIDENCE%20OF%20TUMOR%20CELLS....pdf

Correct surgical therapy considers radical excision of tumor formation, what can be certificated by absence of tumor cells on histopathological specimen margins.The aim of this investigation is to estimate incidence of presence of tumor cells on histopathological specimen margins in cases of intraoral carcinomas, surgically excised in macroscopically normal tissue with different wideness of normal tissue zone and relation to postoperative survival of this patients with intraoral carcinomas.Fifty seven patients with intraoral carcinomas were divided in three groups according to wideness of zone of excision in macroscopically normal tissue. Lowest percent of presence of tumor cells on margins of histopathological specimens were in group of patients with zone of excision behind zone of indurations of soft tissue, but patients from this group had shortest postoperative survival period. Presence of tumor cells on margins of histopathological specimens of excided intraoral carcinomas was found in high number of 81,07%.It can be said that presence of tumor cells on margins of histopathological specimens of exceeded intraoral carcinomas was found in extremely high number of 81,07%, but direct statistical significant relation in-between wideness of surgical excision and postoperative survival period was not found what show that another factors connected with postoperative survival of this patients must be examine.