Proliferation rate and differentiation potential are independent during the transition from neurogenesis to gliogenesis in the mouse embryonic spinal cord

Proliferation rate and differentiation potential are independent during the transition from neurogenesis to gliogenesis in the mouse embryonic spinal cord

Neural stem cells (NSC) restrict their differentiation potential as the central nervous system develops. Experimental evidence suggests that the mechanisms governing the transition from the neurogenic to the gliogenic phase irreversibly affect the ability of NSC to generate neurons. Cell cycle regul...

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Bibliographic Details
Main Authors: Leonora Olivos-Cisneros, Jesús Ramírez-Santos, Gabriel Gutiérrez-Ospina
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:IBRO Neuroscience Reports
Subjects:
Cell cycle
Gliogenesis
Neurogenesis
Neurosphere culture
Spinal cord
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242120000081

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http://www.sciencedirect.com/science/article/pii/S2667242120000081

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